I'm using synthetic 5/50 and it seems to run very smooth. I believe the synthetic is good for many more miles than the regular one. I remember many years ago when they first came out, they were doing tests on engines going 100,000+ miles and taking the engine apart and seeing no appreciable wear. Of course now, they recommend you to change much more often, but I believe you don't need to. I plan to change the filter at regular intervals, but only change the oil annually.